Encapsulation of Menthol in Beeswax by a Supercritical Fluid Technique

dissolution enhancement of glybenclamide by a supercritical fluid-based solvent -antisolvent technique

Polymer Encapsulation of Fine Particles by a Supercritical Antisolvent Process

Coating and encapsulation of fine particles with polymer using a supercritical antisolvent (SAS) coating process was investigated in this research. Synthesized submicron silica particles were used as host particles and poly(lactide-co-glycolide) (PLGA), a biodegradable polymer used for controlled release of drugs, was chosen as the coating material. In the SAS coating process a suspension of si...

Supercritical Fluid Extraction+supercritical Fluid Chromatography

high pressures also requires special equipment. In summary, both RESS crystallization and SAS crystallization appear to be promising methods for generating supersaturation and therefore represent alternatives to conventional crystallization. Such alternatives may prove attractive in applications such as polymer and pharmaceutical processing, or in particle design for drug delivery. It is possib...

Lipidomics by Supercritical Fluid Chromatography

This review enlightens the role of supercritical fluid chromatography (SFC) in the field of lipid analysis. SFC has been popular in the late 1980s and 1990s before almost disappearing due to the commercial success of liquid chromatography (LC). It is only 20 years later that a regain of interest appeared when new commercial instruments were introduced. As SFC is fully compatible with the inject...

Simulation of Separation of a Racemic Mixture of Ibuprofen by Supercritical Fluid Chromatography in Simulated Moving Bed

Separation of a racemic mixture of ibuprofen at a low concentration level by supercritical fluid chromatography in a simulated moving bed (SFC-SMB) is investigated by simulation. The feasibility of ibuprofen enantiomers separation has been experimentally examined in the literature. Our simulation results show that separation of ibuprofen enantiomers is feasible by this method, and R-ibuprofen a...